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Complex organic molecules, such as the bases in RNA, are very fragile and unstable, except at low temperatures. They would not hold together long enough to serve as the first self-replicating proto-life.
Source: Bergman, Jerry. 2000. Why abiogenesis is impossible. Creation Research Society Quarterly 36(4), http://www.creationresearch.org/crsq/articles/36/36_4/abiogenesis.html , Yahya, Harun. 2003. The secrets of DNA http://www.harunyahya.com/dna03.php
